The online home for the primary care professionals managing patients with cardiovascular disease, diabetes and related diseases.

Wednesday, 04 January 2017
Adding evolocumab to optimised statin therapy results in statistically significant regression of atherosclerosis in patients with coronary artery disease, according to results from the GLAGOV phase 3 trial.
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Wednesday, 04 January 2017
Tackling obesity by offering the opportunity to attend a weight loss programme during a routine consultation is effective, welcomed by patients and takes only 30 seconds, according to a new randomised trial of over 1800 people in the UK.
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Wednesday, 21 December 2016
Stroke related to atrial fibrillation can be prevented effectively through the use of anticoagulants. This article reviews recent guidelines, clinical trials and real-world evidence with non-vitamin K antagonist oral anticoagulants (NOACs) in patients with AF and provides practical guidance on the use of these newer agents in primary care.
Category: Editorial
Wednesday, 21 December 2016
‘Issues & Answers in Cardiovascular Disease’ is the leading UK cardiovascular conferences for the whole primary care team. Expert presenters and a down-to-earth approach help health professionals translate the latest evidence into daily practice and optimise patient care. Participants also receive 6 hours CPD credits. Read the highlights from the 2016 conference and access presentation slides here.
Category: Editorial
Monday, 19 December 2016
The UK charity Heart Valve Voice has developed the first practical guidance in heart valve disease for primary care. The disease is under-diagnosed and yet is increasing in prevalence as the population ages, so there is a need for primary care to plan an appropriate response.
Category: Editorial
Thursday, 24 November 2016
The large randomised controlled trial PARADIGM-HF showed that treatment with sacubitril/valsartan (Entresto) compared with enalapril reduced the risk of hospitalisation, cardiovascular and all-cause mortality and improved symptoms in patients with heart failure with reduced ejection fraction. This article describes the key results and how they can be applied in primary care.
Category: Editorial
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Monday, 21 November 2016
HF has a major impact on patients, their families, the NHS and social care services. It still has a poor prognosis, worse than many of the common cancers that also affect older people. It causes significant morbidity and imposes a major cost burden on the health service. This editorial provides an introduction to a special supplement on a first-in-class oral treatment for heart failure.
Category: Editorial
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Thursday, 27 October 2016
Targeting cardiovascular disease risk factors may be important across a person’s lifetime, as a new study from the US National Institutes of Health shows that efforts to prevent risk factors should extend to those over 65 years of age.
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Thursday, 27 October 2016
Semaglutide, an investigational human glucagon-like peptide-1 (GLP-1) analogue, significantly reduced the risk of the primary composite endpoint of time to first occurrence of cardiovascular (CV) death, non-fatal myocardial infarction or non-fatal stroke by 26% vs placebo, when added to standard of care in adults with type 2 diabetes at high CV risk.
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Thursday, 27 October 2016
The benefits of statin therapy have been repeatedly underestimated, and the harms exaggerated, due to misinterpretation of the evidence, according to the authors of a major review published in The Lancet recently.

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